Welcome to the Harwani Lab

Faculty Picture, Sailesh Harwani, MD, PhD

Sailesh Harwani, MD, PhD
Assistant Professor
Dept. of Internal Medicine
Abboud Cardiovascular Research Center

My group's research focuses on the interaction between the nervous system and the immune system/inflammation in hypertension. We are investigating the role of the “neuro-immune axis” in cardiovascular disease and specifically hypertension. Moreover,  we have  the goal of  translating our “bench” discoveries to the “bedside".


Lab Members

Principal Investigator

Sailesh Harwani, MD, PhD
(Faculty Profile)

Research Assistant

Nandita Raikwar


Recent Publications

Macrophages under pressure: the role of macrophage polarization in hypertension. Harwani SC. Translational Research. 2017 Nov 7. doi.org/10.1016/j.trsl.2017.10.011. [Epub ahead of print] 

Nicotine Mediates CD161a+ Renal Macrophage Infiltration and Premature Hypertension in the Spontaneously Hypertensive RatHarwani SC, Ratcliff J, Sutterwala FS, Ballas ZK, Meyerholz DK, Chapleau MW, Abboud FM. Circ Res. 2016 Oct 28;119(10):1101-1115. Epub 2016 Sep 22.

The immune system and hypertension. Singh MV, Chapleau MW, Harwani SC, Abboud FM. Immunol Res. 2014 Aug;59(1-3):243-53. doi: 10.1007/s12026-014-8548-6. Review.

Neurohormonal modulation of the innate immune system is proinflammatory in the prehypertensive spontaneously hypertensive rat, a genetic model of essential hypertension. Harwani SC, Chapleau MW, Legge KL, Ballas ZK, Abboud FM. Circ Res. 2012 Oct 12;111(9):1190-7. doi: 10.1161/CIRCRESAHA.112.277475. Epub 2012 Aug 17.

Autonomic neural regulation of the immune system: implications for hypertension and cardiovascular disease. Abboud FM, Harwani SC, Chapleau MW. Hypertension. 2012 Apr;59(4):755-62. doi: 10.1161/HYPERTENSIONAHA.111.186833. Epub 2012 Feb 13. Review.

Complete list of publications